Moderate Coffee Consumption Linked to Lower Risk of Cardiometabolic Diseases

New research published in the Journal of Clinical Endocrinology & Metabolism suggests that #regular, moderate coffee or #caffeine intake may reduce the risk of developing multiple cardiometabolic diseases, including type 2 diabetes, coronary heart disease, and stroke.

The study, led by Dr. Chaofu Ke from Suzhou Medical College, found that consuming three cups of coffee (or 200-300 mg of caffeine) daily was associated with a 40-48% lower risk of developing cardiometabolic multimorbidity (CM)—the coexistence of two or more cardiometabolic conditions. The research highlights the protective role of coffee and caffeine throughout the stages of CM development.

Researchers used data from the UK Biobank, a large dietary study with over 500,000 participants aged 37-73. The analysis focused on 172,315 individuals who were free of cardiometabolic diseases at the start. The study found that moderate coffee or caffeine consumption was inversely related to new cases of CM, with moderate consumers showing the lowest risk.

This research fills a gap by examining the effects of coffee and caffeine on multiple cardiometabolic diseases, rather than individual conditions. Dr. Ke noted that promoting moderate coffee or caffeine intake could offer significant benefits for preventing CM and reducing mortality risks, as individuals with CM face 4 to 7 times higher mortality rates than those without these conditions.

The findings suggest that incorporating moderate coffee or caffeine consumption into dietary habits may help protect against serious health risks.

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Reference: 

Xujia Lu et al. Habitual Coffee, Tea and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity. JCEM, 2024 DOI: 10.1210/clinem/dgae552